Resin lipid nanoparticles are embedded in the eyeballs: an effective strategy to improve eye transmi

An international medical study has brought new findings and related findings have important reference value for disease prevention. Rebamipide is used to treat dry eye disease. Rebamipide is widely used in eye care in Japan.

However, some of the challenges observed include blurred vision, less permeability due to large particle size, frequent local droplets, and bitter taste. Thus, in this study, REBA-NS nanoparticles (REBA-NS) and their preparation methods (REBA-NS) based on embedded gelatin and using HPMC as a stabilizer and optimizing the use of quality-type design) were developed to address the challenges and application convenience of REBA-NS nanoparticles and their preparation methods. After contact with the simulated liquid, REBA-NS shows nanoparticles with a diameter of <270 nm, which may contribute to enhanced penetration and low polydispersity index (<0.

2). It should be noted that the above information is based on international public research and is for reference by HealthCop and does not constitute clinical advice.